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Atherosclerosis

As atherosclerosis is by far the most common cause of arterial disease, it is worth while to discuss this disease process in more detail.

While a patient may present with a complaint of leg pain while walking due to blockage of his or her leg arteries, the most relevant factor may not be the leg pain, but an increased risk of heart attack or stroke. This is because atherosclerosis in one area (such as a leg artery) may imply atherosclerosis in another area (such as in an artery supplying the heart or brain).

Accordingly, when seeing patients with an arterial blockage due to atherosclerosis in one area of the body, it is frequently necessary to spend time discussing atherosclerosis in general, not only as to how it relates to the presenting problem.

Atherosclerosis has several known risk factors, which means items in an individual’s medical history that are more common in those with atherosclerosis than in those without atherosclerosis. A patient with atherosclerosis typically will not have all of these risk factors, and rarely, some will have none, but most patients with atherosclerosis will have at least some.

The common risk factors are:

  • Family History (peripheral arterial disease, heart attack, stroke, etc.)
  • Hypertension (elevated blood pressure)
  • Hyperlipidemia (elevated cholesterol or other fatty elements in the blood)
  • Diabetes (sometimes undiagnosed)
  • Tobacco use (past or current)
  • Obesity
  • Sedentary lifestyle
  • Age (like many things, atherosclerosis becomes more significant as we age)

Therefore, in addition to managing the presenting problem, one must also ensure that patients are educated regarding atherosclerosis and its risk factors, and that any correctable risk factors are appropriately addressed.

Many patients with atherosclerosis will benefit from certain interventions, such as a better diet, more exercise, weight loss, and cessation of tobacco use. In addition, many patients will also benefit from the addition of specific
medications, such as Aspirin or similar agents designed to affect platelets (elements in blood responsible for clotting) and Statin therapy for control of hyperlipidemia. It is worthwhile to remember that while a given patient’s blood pressure, glucose and/or cholesterol levels may be “normal” (compared to the general population, with and without a diagnosis of atherosclerosis), it may be too high for them, given the fact that they have atherosclerosis.

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